Clinical and Diagnostic Virology

Diagnostic virology is rapidly growing into the mainstream of clinical medicine as a result of the convergence of several independent developments. First, dramatic progress in antiviral therapeutics has increased the need for specific viral diagnoses. Second, technological advancements particularly in the area of nucleic acid chemistry, have provided important new tools for viral diagnosis. Third, the number of patients at risk for opportunistic viral infections has expanded greatly as a result of the HIV/AIDS epidemic. Finally, modern disease management of HIV infection and hepatitis C is providing a new paradigm for the integration of molecular techniques into the management of chronic viral infections. These developments are not only increase the use of diagnostic virology but are reshaping the field. The purpose of this article is to review the field of diagnostic virology at the beginning of the 21st century, to provide guidance about current use of the tools of diagnostic virology, and to provide a glimpse of important future developments.


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